Welcome to the website of the Computational Biology Lab

About our research

Computational Neuroscience Projects

We are interested in understanding how dendrites and their integrative properties contribute to learning and memory functions. Towards this goal, we build abstract mathematical as well as detailed biophysical models of neural cells and circuits across multiple brain regions (hippocampus, amygdala, PFC) and abstraction levels (single neurons, microcircuits, neuronal networks). We then use the models to study how the anatomical, biophysical and plasticity properties of dendrites contribute to memory functions.

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Bioinformatics Projects

We focus on developing computational methods and tools for (a) analyzing large-scale gene expression data related to human cancer in search for gene markers and disease sub-categories, (b) identifying regulatory elements such as miRNA precursors and their targets in whole genomes of plants and mammals, (c) building theoretical models of gene regulatory networks. Our methodological approaches include (a) novel clustering and feature selection algorithms, (b) machine learning algorithms such as artificial neural networks, hidden Markov models etc.

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Outreach

WEF ERC IdeasLab 2014

 

 

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Latest News

#isiCNI2019, here comes Ioanna!

Congratulations to Master's student Ioanna Pandi for being selected to attend the highly competitive IBRO-SIMONS Computational Neuroscience Imbizo (2019) school in Cape Town, South Africa.

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Dr. Papoutsi awarded with the prestigious NARSAD 2018 Young Investigator Grant

"Athanasia Papoutsi, Ph.D., will be taking a closer look at the cells in the prefrontal cortex of the brain to determine whether modifications of the “spines” in single neurons ... ". Read the full announcement. 

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The ERC dEMORY project featured as webcomics

Science meets art, art meets science! ERCcOMICS has featured dEMORY as a notable ERC-funded research project ...

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Successful completion of DENDRITES 2018 EMBO meeting

The 3rd EMBO Workshop on Dendrites was completed with great success...

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Investing in Young Researchers, Shaping Europe’s Future

23 ERC grantee researchers, Dr. Poirazi included, 3 Nobel Laureates, and MEPs met at Strasbourg on 31 May to address current science policy issues and shape the future directions of European Research.

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Funding