Welcome to the website of the Computational Biology Lab

About our research

Computational Neuroscience Projects

We are interested in understanding how dendrites and their integrative properties contribute to learning and memory functions. Towards this goal, we build abstract mathematical as well as detailed biophysical models of neural cells and circuits across multiple brain regions (hippocampus, amygdala, PFC) and abstraction levels (single neurons, microcircuits, neuronal networks). We then use the models to study how the anatomical, biophysical and plasticity properties of dendrites contribute to memory functions.

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Bioinformatics Projects

We focus on developing computational methods and tools for (a) analyzing large-scale gene expression data related to human cancer in search for gene markers and disease sub-categories, (b) identifying regulatory elements such as miRNA precursors and their targets in whole genomes of plants and mammals, (c) building theoretical models of gene regulatory networks. Our methodological approaches include (a) novel clustering and feature selection algorithms, (b) machine learning algorithms such as artificial neural networks, hidden Markov models etc.

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Outreach

WEF ERC IdeasLab 2014

 

 

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Latest News

Linking memories with synaptic capture and excitability

Dr. Kastellakis's research on the cellular mechanisms that facilitate learning and memory is gaining momentum...

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Successful completion of DENDRITES 2018 EMBO meeting

The 3rd EMBO Workshop on Dendrites was completed with great success...

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Investing in Young Researchers, Shaping Europe’s Future

23 ERC grantee researchers, Dr. Poirazi included, 3 Nobel Laureates, and MEPs met at Strasbourg on 31 May to address current science policy issues and shape the future directions of European Research.

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Alexandra Tzilivaki was selected as Next Generation Woman Leader by McKinsey and Company

Our lab member Alexandra Tzilivaki, PhD candidate at Charite Medical School Berlin and IMBB FORTH, was recently appointed as Next Generation Woman Leader by McKinsey & Company.

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Dr. Papoutsi, along with Dr. Mari, receive the highly competitive ELIDEK (HFRI) grant

The young investigators will benefit from the ELIDEK (HFRI) financial support to establish novel and multi-disciplinary neuroscience research at our host institute, IMBB-FORTH.

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Funding