About our research

Computational Neuroscience

We are interested in understanding how dendrites and their integrative properties contribute to learning and memory functions. Towards this goal, we build abstract mathematical as well as detailed biophysical models of neural cells and circuits across multiple brain regions (hippocampus, amygdala, PFC) and abstraction levels (single neurons, microcircuits, neuronal networks). We then use the models to study how the anatomical, biophysical and plasticity properties of dendrites contribute to memory functions.

 

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Experimental Neuroscience

Our lab has recently expanded its research activities to include experiments in mice. Using head-fixed behavioral set-ups, in vivo imaging and electrophysiology, our primary goal is to probe dendritic contributions to neuronal and circuit computations as well as behavior. Current projects focus on the role of dendritic nonlinearities in the prefrontal cortex and the animal's ability to exhibit behavioral flexibility. 
 

For more details on our experimental projects visit the links below:
 

NARSAD/ELIDEK & EINSTEIN

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Outreach

Συνενέντευξη της Δρ. Ποϊράζη στο protagon.gr σχετικά με την έρευνα που διεξάγεται στο εργαστήριο, με ειδικό αφιέρωμα στα αποτελέσματα της πρόσφατης συνεργασίας με το εργαστήριο του Dr. Losonczy στο Πανεπιστήμιο του Columbia.


Dr. Poirazi representing the European Research Council at World Economic Forum.

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Latest News

Our most exhaustive review (yet) on dendritic modeling in now published in Nature Reviews Neuroscience

We are excited to announce the publication of the most exhaustive review we’ve written on the subject yet. Co-authored by Prof. Poirazi and Dr. Papoutsi, the offer a comprehensive view of field-defining modeling studies, organized in ...

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Our latest collaborative study is now published in Nature Neuroscience

Congratulations to our post-doc researcher Dr. Chavlis and PhD student Ioanna Pandi!

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Quanta Magazine runs a story covering our recent Science paper

Quanta Magazine is published by the Simons Foundation and covers developments in the fields of physics, mathematics, biology, and computer science.

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New Science paper is now online. Check it out!

Our latest collaborative work with the Larkum lab offers new insights into the dendritic computations of the human brain.

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Feature selectivity in visual cortex: Our collaborative work with the Smirnakis lab is published in Nature Communications

Ever wondered how individual dendrites contribute to orientation tunings? Wonder no more. Check out our latest publication and see how neuronal modeling can guide / aid advanced new technologies in lab experimentation ...

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Deep Learning - New Perspective in Nature Neuroscience

Together with a group of amazing scientists, we recently wrote a Perspective on how Deep Learning principles may help advance Neuroscience and vise-versa. It started as heated discussions in a meeting in ...

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Funding