An exciting collaborative study where our lab provided modelling insights is out in Neuron. The study entitled “Cell-Specific Dendritic Integration in Cortical GABAergic Interneurons,” reveals that PV- and SST-expressing interneurons process information in fundamentally different ways. SST interneurons show supralinear integration and uniform synaptic distribution, supporting broad temporal integration and sustained activity. In contrast, PV interneurons exhibit sublinear integration and denser […]
Tag Archives: Interneurons
Uncovering the mechanisms of spatial deficits in epilepsy
Epilepsy’s impact is not limited to seizure events While most seizures resolve spontaneously after a few minutes, the long-term impact can be rather grim if the condition goes untreated. Significant memory and executive function deficits often ensue, taking a toll on patients’ daily lives. This is no surprise since the most common diagnosis for epilepsy involves […]