Dendritic Plasticity: A Key Mechanism in Memory Integration

A new study published in Nature Neuroscience sheds light on the critical role of dendritic plasticity in linking memories.  Researchers found that when two events occur close in time, the brain tends to link them together using specific dendritic mechanisms.  This research demonstrates that linked memories activate the same dendritic segments and that new spine clusters are allocated to these shared dendritic segments. This publication results from a collaborative research project involving the Silva lab at UCLA, the Sehgal lab at OSU, and the Poirazi Lab at IMBB-FORTH.  Dr. George Kastellakis, a postdoctoral researcher in the Poirazi Lab at IMBB-FORTH, contributed to this study under the supervision of Dr. Panayiota Poirazi.

Find out more regarding the paper here.