A collaborative study between the Vassanelli and Poirazi Labs presented a new method for understanding functional connectivity in neuronal cultures. The study used Interventional Connectivity (IC) to probe neuronal activity in cultures grown on High-Density Multi-Electrode Arrays (HD-MEAs) and revealed that the network’s causal architecture can be reliably predicted from its spontaneous activity.
This approach offers a practical method for analyzing neuronal networks and designing targeted experiments in vitro. Read the full paper here. The work was a result of the NEUREKA project.
